pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16; ATP-dependent RNA helicase DHX38; DEAH box protein 38 (DHX38, DDX38, KIAA0224, PRP16)

Function: - ATP-binding RNA helicase involved in pre-mRNA splicing (putative) - identified in the spliceosome C complex Structure: - belongs to the DEAD box helicase family, DEAH subfamily, PRP16 sub-subfamily - contains 1 helicase ATP-binding domain - contains 1 helicase C-terminal domain Compartment: nucleus (putative)

General

DEAH box ATP-dependent helicase phosphoprotein splicing factor; snRNP-associated protein

Properties

SIZE: entity length = 1227 aa MW = 141 kD COMPARTMENT: cell nucleus MOTIF: helicase NAME: helicase SITE: 542-705 MOTIF: ATP-binding site NAME: ATP-binding site SITE: 555-562 DEAD/H box NAME: DEAD/H box SITE: 652-655 Helicase C-terminal {727-902} Ser phosphorylation site {S1194}

Database Correlations

OMIM 605584 UniProt Q92620 PFAM correlations Entrez Gene 9785 Kegg hsa:9785 ENZYME 3.6.4.13

References

UniProt :accession Q92620