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dentate granule neuron
Function:
- granule cells of the dentate gyrus the principle neurons of the granule cell layer, a layer with a prominant dendritic arborization (molecular layer)
- the hilus of the dentate gyrus contains neuroblasts that form granule cells from birth into old age.
- newly formed granule cells accumulate under the older granule cells gradually increasing the thickness of the granule layer throughout life [2]
* The human dentate gyrus contains about 9 x 10E6 granule cells.
Comparative biology:
- dentate granule cells of the rat have apical dendrites only
- many dentate granule cells in humans & monkeys also have basal dendrites [2]
Afferents:
- entorhinal cortex (perforant pathway)
Efferents:
1) cornu ammonis CA3 pyramidal cells (mossy fiber pathway)
2) cells of the of the dentate gyrus do not project outside of the hippocampal formation
Related
dentate gyrus
General
granule cell
Properties
WITHIN: dentate gyrus
References
- AGE/AFAR Meeting, May 31-June 4, 2001, Madison, WI
- Wikipedia: Dentate gyrus
https://en.wikipedia.org/wiki/Dentate_gyrus