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dengue virus
Pathology:
- etiologic agent of Dengue fever
- dengue NS1 protein
Laboratory:
- dengue virus serology (at least 4 serotypes)
- dengue virus antigen
- NS1 tests detect the non-structural protein 1 (NS1) of dengue virus
- NS1 is secreted into the blood during a dengue infection
- presence of NS1 in blood is consistent with acute phase dengue infection
- dengue virus RNA
- dengue + chikungunya + zika virus RNA
Comparative biology:
- also occurs in monkeys & chimpanzees, generally as asymptomatic infection
Structure:
- size: 50 nm in diameter
Related
Dengue virus antibody in serum
dengue virus vaccine (Dengvaxia)
dengue; bone break fever; dandy fever; Duengero fever; 7 day fever
General
flaviviridae
arbovirus
Properties
KINGDOM: virus
GENOME-TYPE: RNA
SINGLE-STRANDED
NEGATIVE-STRAND
GENOME-SIZE: 10 kB
ENVELOPE: PRESENT
CAPSID-SYMMETRY: ICOSAHEDRAL