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dendritic cell
Function:
- antigen-presenting cells
- dendritic cells capture & process antigens from microorganisms in peripheral tissues, migrate to lymphoid organs, secrete cytokines to initiate immune responses & present the antigens to resting T cells
- dendritic cells are present in tissues in contact with the external environment
- all dendritic cells are ultimately of bone marrow origin.
- thymic dendritic cells & T cells develop simultaneously in the thymus from a common precursor population
Related
dendritic cell neoplasm
Specific
dendritic cell precursor type 2 (plasmacytoid dendritic cell, natural interferon (IFN)-producing cells, pre-DC2, pDC)
Langerhan's cell
General
antigen-presenting cell (APC)
epithelial cell
References
- Ardavin C et al.
Thymic dendritic cells and T cells develop simultaneously in
the thymus from a common precursor population.
Nature 362:761 1993
PMID: 8469288
- Banchereau J & Steinman RM
Dendritic cells and the control of immunity.
Nature 392:245-52, 1998
PMID: 9521319
- UniProt :accession O95715
- Wikipedia: Dendritic dell
http://en.wikipedia.org/wiki/Dendritic_cell