Search
Demons-Meigs syndrome
benign ovarian disease associated with a pleural effusion
Pathology:
- ovarian fibroma* (most common)
- fibrothecoma
- ascites
- pleural effusion
* only 1-2% of patients with ovarian fibroma present with Demons-Meigs syndrome
Clinical manifestations:
- abnormal uterine bleeding (case report) [1]
Laboratory:
- serum CA125 often elevated
Differential diagnosis:
- ovarian cancer
Management:
- surgical resection (TAH-BSO) of the ovarian fibroma results in permanent resolution of the pleural effusion [1]
General
syndrome
References
- Ray A, Masch WR, Saukkonen K, Harrison BT.
CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL.
Case 18-2016. A 52-Year-Old Woman with a Pleural Effusion
N Engl J Med. 2016 Jun 16;374(24):2378-87
PMID: 27305196
http://www.nejm.org/doi/full/10.1056/NEJMcpc1600612