dehydrogenase

Includes some lyases, although most are oxidoreductases.

Specific

15-hydroxyprostaglandin dehydrogenase [NAD+]; PGDH; prostaglandin dehydrogenase 1 (HPGD, PGDH1) 2,4-dienoyl CoA reductase 2-oxoglutarate dehydrogenase, mitochondrial; 2-oxoglutarate dehydrogenase complex component E1; OGDC-E1; alpha-ketoglutarate dehydrogenase (OGDH) 3-beta hydroxy-5-ene steroid dehydrogenase type 1; steroid delta isomerase; progesterone reductase (HSD3B1, HSDB3A) 3-beta hydroxy-5-ene steroid dehydrogenase type 2; steroid delta isomerase; progesterone reductase (HSD3B2) 3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) 3-keto-steroid reductase (estradiol 17-beta-dehydrogenase 7, 17-beta-HSD 7, 17-beta-hydroxysteroid dehydrogenase 7, HSD17B7) 3-OH acyl CoA dehydrogenase 3-OH butyrate dehydrogenase; beta-hydroxybutyrate dehydrogenase (BDH1) 3-oxo-5-alpha-steroid 4 dehydrogenase; steroid 5-alpha reductase; testosterone 5-alpha reductase acyl CoA dehydrogenase alanine dehydrogenase alcohol dehydrogenase (aldehyde reductase) aldehyde dehydrogenase aldo-keto reductase family 1 member A1; alcohol dehydrogenase NADP+; aldehyde reductase (AKR1A1, ALDR1, ALR) alpha-aminoadipic semialdehyde synthase, mitochondrial; LKR/SDH; includes: lysine ketoglutarate reductase; LKR; LOR; saccharopine dehydrogenase; SDH (AASS) alpha-ketoglutarate dehydrogenase aspartate semialdehyde dehydrogenase bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 (NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein, [includes: NAD-dependent methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase], MTHFD2L) bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; includes: NAD-dependent methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase (MTHFD2, NMDMC) branched-chain keto acid dehydrogenase E1 or 2-oxoisovalerate dehydrogenase branched-chain ketoacid dehydrogenase C-terminal-binding protein 1 (CtBP1, CTBP) C-terminal-binding protein 2 (CtBP2) carbohydrate dehydrogenase carbonyl reductase [NADPH] 3 (NADPH-dependent carbonyl reductase 3, CBR3) choline dehydrogenase, mitochondrial; CDH (CHDH) cytosolic 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; FDH; aldehyde dehydrogenase family 1 member L1 (ALDH1L1, FTHFD) D-2-hydroxyglutarate dehydrogenase, mitochondrial (D2HGDH) D-3-phosphoglycerate dehydrogenase; 3-PGDH (PHGDH, PGDH3) dehydrogenase/reductase SDR family (DHRS) dehydrogenase/reductase SDR family member 12 (DHRS12) dehydrogenase/reductase SDR family member 13 (DHRS13) dehydrogenase/reductase SDR family member 4-like 2 (DHRS4L2) dehydrogenase/reductase SDR family member 7B (DHRS7B) delta-1-pyrroline-5-carboxylate synthase; P5CS; aldehyde dehydrogenase family 18 member A1; includes: glutamate 5-kinase; GK; gamma-glutamyl kinase; gamma-glutamyl phosphate reductase; GPR; glutamate-5-semialdehyde dehydrogenase; glutamyl-gamma-semialdehyde dehydrogenase (ALDH18A1, GSAS, P5CS, PYCS) delta-6 fatty acid desaturase complex dihydrodiol dehydrogenase dihydrofolate reductase (DHFR, tetrahydrofolate dehydrogenase) dihydroorotate dehydrogenase, mitochondrial; DHOdehase; dihydroorotate oxidase (DHODH) dihydropyrimidine dehydrogenase; DHPDHase; dihydrouracil dehydrogenase; dihydrothymine dehydrogenase (DPD, DPYD) dimethylglycine dehydrogenase, mitochondrial (ME2GLYDH, DMGDH) electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial; ETF-ubiquinone oxidoreductase; ETF-QO; electron-transferring-flavoprotein dehydrogenase; ETF dehydrogenase (ETFDH) epidermal retinal dehydrogenase 2; RDH-E2; EPHD-2; retinal short chain dehydrogenase reductase 2; retSDR2 (RDHE2, SDR16C5) fatty acid desaturase 1 (delta(5) fatty acid desaturase, selta(5) desaturase, D5D, FADS1, FADSD5) fatty acid desaturase 2 (delta(6) fatty acid desaturase, delta(6) desaturase, D6D, FADS2) fatty acid desaturase 2-like protein (FADS2P1) fatty acid desaturase 3 (cytochrome b5-related protein, FADS3, CYB5RP) formyltetrahydrofolate dehydrogenase GDH/6PGL endoplasmic bifunctional protein; endoplasmic bifunctional protein precursor [Includes: glucose 1-dehydrogenase, hexose-6-phosphate dehydrogenase, 6-phosphogluconolactonase] (6PGL, H6PD, G1DH) glutamate dehydrogenase (GDH) Glutaryl-CoA dehydrogenase, mitochondrial (GCD, GCDH) glyceraldehyde-3-phosphate dehydrogenase (GAPDH, GAPD, CDABP0047, OK/SW-cl12) glycerol-3-phosphate dehydrogenase hematopoietic prostaglandin D synthase; H-PGDS; GST class-sigma; glutathione S-transferase; glutathione-dependent PGD synthase; glutathione-requiring prostaglandin D synthase; prostaglandin-H2 D-isomerase (HPGDS, GSTS, PGDS, PTGDS2) homoserine dehydrogenase hydroxysteroid dehydrogenase hydroxysteroid dehydrogenase-like protein 1 (HSDL1) hydroxysteroid dehydrogenase-like protein 2 (HSDL2) inosine 5' monophosphate [IMP] dehydrogenase isobutyryl-CoA dehydrogenase, mitochondrial; activator-recruited cofactor 42 kD component; ARC42; acyl-CoA dehydrogenase family member 8; ACAD-8 (ACAD8, ARC42, IBD) isocitrate dehydrogenase isovaleryl CoA dehydrogenase (IVD) L-2-hydroxyglutarate dehydrogenase, mitochondrial (duranin, L2HGDH, C14orf160) L-aspartate dehydrogenase (ASPDH, ASPD) L-lactate dehydrogenase A-like 6A (LDHAL6A, LDHL2) lactate dehydrogenase (LDH) leucine dehydrogenase lipoamide dehydrogenase (glycine cleavage system L protein, DLD, GCSL, LAD, LADH, PHE3) malate dehydrogenase NADH dehydrogenase; respiratory chain complex-I; NADH CoQ reductase;NADH-ubiquinone oxidoreductase NADP+ transhydrogenase mitochondrial; pyridine nucleotide transhydrogenase, nicotinamide nucleotide transhydrogenase (NNT) NADPH-dependent carbonyl reductase; prostaglandin-E2 9-reductase; 15-hydroxyprostaglandin dehydrogenase [NADP+] (CBR1, CBR, CRN) orphan short-chain dehydrogenase/reductase; SDR-O; RDH-S (SDRO, SDR9C7, RDHS) phenylalanine dehydrogenase proline dehydrogenase 2 (kidney & liver proline oxidase 1, HsPOX1, PRODH2) proline oxidase (proline dehydrogenase, PRODH) prostaglandin reductase 1; PRG-1; 15-oxoprostaglandin 13-reductase; NADP-dependent leukotriene B4 12-hydroxydehydrogenase (PTGR1, LTB4DH) pyruvate dehydrogenase pyruvate dehydrogenase E1 saccharopine dehydrogenase SCCPDH (SCCPDH) sarcosine dehydrogenase, mitochondrial (SarDH, BPR-2) short-chain dehydrogenase/reductase 3; DD83.1; retinal short-chain dehydrogenase/reductase 1; retSDR1 (DHRS3) stearoyl-CoA desaturase; fatty acid desaturase; delta(9)-desaturase (SCD, SCD1) sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; protein H105e3 (NSDHL, H105E3) succinate dehydrogenase (mitochondrial complex 2) trifunctional enzyme beta subunit, mitochondrial; TP-beta; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase beta subunit (HADHB) UDP-glucose 6-dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH (UGDH) xanthine dehydrogenase (XDH, XDHA)

Properties

MOTIF: active site