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Carbamide peroxide otic (Debrox, Murine ear, Auro)
Tradenames: Debrox, Murine ear, Auro.
Indications:
- emulsification & dispersion of ear wax
a) prior to ear lavage
b) home use for patients with chronic cerumen impactation
Dosage:
1) 5-10 drops BID for up to 4 days
2) allow dose to remain in ear for 15 minutes
3) follow by rinsing ear canal with warm water 30 mL bottle.
Adverse effects:
1) irritation
2) superinfection
Mechanism of action:
- hydrogen peroxide loosens ear wax due to foaming action
General
Carbamide peroxide
otic agent; otologic agent; ear preparation
Database Correlations
PUBCHEM cid=31294
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Drug Information & Medication Formulary, Veterans Affairs,
Central California Health Care System, 1st ed., Ravnan et al
eds, 1998
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998