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dynactin subunit 4 (dynactin subunit p62, DCTN4)
Function:
- dual role in dynein targeting & in ACTR1A/Arp1 subunit of dynactin pointed-end capping (putative)
- role in ACTR1A pointed-end binding & in linking dynein & dynactin to the cortical cytoskeleton (putative)
- member of the pointed-end complex of the dynactin shoulder complex
- binds directly to the ACTR1A subunit of dynactin
Structure: belongs to the dynactin subunit 4 family
Compartment:
- cytoplasm, centrosome
- punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin
- may be targeted to the nucleus with very high expression
General
protein subunit
Properties
SIZE: MW = 52 kD
entity length = 460 aa
COMPARTMENT: cytoplasm
cell nucleus
golgi
MOTIF: coiled coil {152-172}
Database Correlations
UniProt Q9UJW0
Pfam PF05502
Kegg hsa:5116
References
UniProt :accession Q9UJW0