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cytochrome P450 3A (CYP3A)
Most common cyt P450 form involved in pharmaceutical metabolism. Drug metabolism is best exemplified by cytochrome P450 3A4.
Specific
cytochrome P450 3A4 (cytochrome P450 C3, nifedipine oxidase, P450-PCN1, NF-25, CYP3A4)
cytochrome P450 3A43 (CYP3A43)
cytochrome P450 3A5 (P450-PCN3, CYP3A5)
cytochrome P450 3A7 (P450-HFLA, CYP3A7)
General
cytochrome P450
Properties
COMPARTMENT: smooth endoplasmic reticulum
MOTIF: membrane region
heme-binding site [cysteine residue]
COFACTOR-BOUND: heme
Database Correlations
Entrez Gene 1574
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, American
College of Physicians, Philadelphia 1998