Search
cytochrome P450 4F2 (leukotriene-B4 omega-hydroxylase, leukotriene-B4 20-monooxygenase, cytochrome P450-LTB-omega, CYP4F2)
Function:
1) NADPH-dependent electron transport pathway
2) oxidizes a variety of structurally unrelated compounds, including
- steroids, fatty acids, xenobiotics
Structure: belongs to the cytochrome P450 family
Compartment: membrane-bound, endoplasmic reticulum
Expression: expressed in liver
Laboratory:
- CYP4F2 enzyme activity
General
cytochrome P450
Properties
SIZE: MW = 60 kD
entity length = 520 aa
COMPARTMENT: endoplasmic reticulum
MOTIF: heme-binding site [328-328]
Iron [Fe]-binding site
SITE: 468-468
Database Correlations
OMIM 604426
UniProt P78329
Pfam PF00067
Entrez Gene 8529
Kegg hsa:8529
ENZYME 1.14.13.30
References
- UniProt :accession P78329