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CYP2D6 & CYP2C19 genotyping panel

Indications: - evaluation of patients for amitriptyline therapy Clinical significance: - CPIC recommends alternative drug to amitrityline for CYP2D6 or CYP2C19 ultrarapid metabolizers & for CYP2D6 poor metabolizers [1]

General

chemistry panel

References

  1. Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline information for amitriptyline and CYP2C19, CYP2D6. https://www.pharmgkb.org/guideline/PA166105006

Components

CYP2C19 genotyping; CYP2C19 allele testing CYP2D6 genotyping