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cyclin G2 (CCNG2)
Function:
- may play a role in growth regulation
- negative regulation of cell cycle progression
Structure: belongs to the cyclin family, cyclin G subfamily
Compartment: cytoplasm (putative)
Expression:
- high levels in cerebellum, thymus, spleen & prostate
- low levels in skeletal muscle
- expression levels increase through the cell cycle to peak in the mid/late-S phase & decrease during G2/M phase
- activated by actinomycin-D induced DNA damage
General
cyclin G
Properties
SIZE: entity length = 344 aa
MW = 39 kD
COMPARTMENT: cytoplasm
MOTIF: Ser phosphorylation site {S220}
Ser phosphorylation site {S234}
Database Correlations
OMIM 603203
UniProt Q16589
Entrez Gene 901
References
UniProt :accession Q16589