cyclin D2 (CCND2)

Function: - essential for the control of the cell cycle at the G1/S (start) transition - interacts with the CDK4 & CDK6 protein kinases to form a serine/threonine kinase holoenzyme complex - the cyclin subunit imparts substrate specificity to the complex Structure: - belongs to the cyclin family, cyclin D subfamily

Properties

SIZE: MW = 33 kD entity length = 289 aa COMPARTMENT: cytoplasm CELL-CYCLE: G1/S MOTIF: ubiquitination site (destruction box, D-box) SITE: N-TERMINAL FOR-BINDING-OF: ubiquitin PEST region cyclin box FOR-BINDING-OF: cyclin-dependent kinase LXC motif FOR-BINDING-OF: retinoblastoma-associated protein

Database Correlations

OMIM 123833 UniProt P30279 PFAM correlations Entrez Gene 894 Kegg hsa:894

References

UniProt :accession P30279