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cardiotrophin-1 (CT-1, CTF1)
Function:
1) induces cardiac myocyte hypertrophy in vitro
2) binds to & activates the ILST/gp130 receptor
Structure:
- belongs to the IL-6 superfamily
Compartment: secreted
Expression:
- expressed in heart, skeletal muscle, prostate, ovary > lung, kidney, pancreas, thymus, testis and small intestine
- little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes
General
other protein
Properties
SIZE: MW = 21 kD
entity length = 201 aa
Database Correlations
OMIM 600435
UniProt Q16619
Pfam PF06875
References
UniProt :accession Q16619