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CSF cell count

see CSF analysis Reference interval: - 0-5 cells/uL (adults) - 0-30 cells/uL, 0-12 cells/uL [2] (neonates) - differential - lymphocytes 62% +/- 34% - monocytes 36% +/- 20% - neutrophils 2% +/- 5% Clinical significance: 1) 500-10,000/mm3 with predominance of neutrophils in bacterial meningitis 2) 10-500/mm3 with predominance of lymphocytes in tuberculous meningitis or fungal meningitis 3) > 6 lymphocytes/mm3 in viral meningitis 4) 10-500/mm3 with predominance of lymphocytes in meningeal carcinomatosis 5) 1000-3,500,000/mm3 RBCs with RBC:WBC ratio higher than peripheral blood in subarachnoid hemorrhage 6) fewer RBC in collection tube 4 than collection tube 1 in traumatic tap 7) 0-20 lymphocytes/mm3 in multiple sclerosis 8) < 5 mononuclear cells/mm3 (normal pattern) in Guillain-Barre & pseudotumor cerebri Specimen: - tube # 3 of CSF analysis

Specific

ependymal+choroid plexus cells in CSF erythrocytes in CSF leukocytes in CSF

General

cell count cerebrospinal fluid analysis hematology panel

References

  1. see CSF analysis, cell count
  2. Byington CL et al. Normative cerebrospinal fluid profiles in febrile infants. J Pediatr 2011 Jan; 158:130. PMID: 20801462

Component-of

cerebrospinal fluid analysis

Components

lymphocytes in CSF neutrophils in CSF