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amyloid-beta peptide in CSF
Notes:
- CSF-based estimates of beta-amyloid using adjusted data-driven cutoffs are ~10% higher than PET-based estimates in people without dementia
- results are similar among people with dementia
- all CSF amyloid-beta isoforms lower in patients with cerebral amyloid angiopathy than in controls
Related
A4 amyloid peptide; beta-peptide
Specific
amyloid-beta peptide 38 in CSF
amyloid-beta peptide 40 in CSF
amyloid-beta peptide 42 in CSF
General
amyloid-beta peptide in body fluid
References
- Jansen WJ, Janssen O, Tijms BM et al
Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease
Clinical Spectrum
JAMA Neurol. 2022;79(3):228-243
PMID: 35099509
https://jamanetwork.com/journals/jamaneurology/fullarticle/2788270
- De Kort AM et al.
Decreased cerebrospinal fluid amyloid beta 38, 40, 42, and 43 levels in sporadic
and hereditary cerebral amyloid angiopathy.
Ann Neurol 2023 Jan 27; [e-pub]
PMID: 36707720
https://onlinelibrary.wiley.com/doi/10.1002/ana.26610