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alpha-crystallin


General

chaperonin; chaperone crystallin multisubunit protein

Properties

COMPARTMENT: tissue WITHIN: intraocular lens SUBUNITS: alpha-crystallin A chain MOTIF: acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl Thr phosphorylation site {T13} tyrosine residue {18} tyrosine residue {34} Ser phosphorylation site {S45} Ser phosphorylation site {S122} cysteine residue {C131} MODIFICATION: cysteine residue {C142} methionine residue {138} Thr phosphorylation site {T140} cysteine residue {C142} MODIFICATION: cysteine residue {C131} Ser glycosylation site {S162} alpha-crystallin B chain MOTIF: acetylation site SITE: N-TERMINUS EFFECTOR-BOUND: acetyl Ser phosphorylation site {S19} Ser phosphorylation site {S21} Ser phosphorylation site {S43} Ser phosphorylation site {S45} tyrosine residue {48} Ser phosphorylation site {S53} Ser phosphorylation site {S59} tryptophan residue {60} methionine residue {68} Ser phosphorylation site {S76} Thr glycosylation site {T170}

Database Correlations

OMIM 123580 MORBIDMAP 123580

References

  1. OMIM :accession 123580

Components

alpha-crystallin A chain; heat shock protein beta-4; HspB4 (CRYAA, CRYA1, HSPB4) alpha-crystallin B chain; alpha(B)-crystallin; heat shock protein beta-5; HspB5; renal carcinoma antigen NY-REN-27; Rosenthal fiber component (CRYAB CRYA2)