dihydropyrimidinase-related protein 5; DRP-5; CRMP3-associated molecule; CRAM; collapsin response mediator protein 5; CRMP-5; UNC33-like phosphoprotein 6; ULIP-6 (DPYSL5, CRMP5, ULIP6)

Function: - may have a role in neuronal differentiation &/or axon growth - homotetramer, & heterotetramer with other DPYS-like proteins - interacts with DPYSL2, DPYSL3 & DPYSL4 Structure: - belongs to the DHOase family hydantoinase/dihydropyrimidinase subfamily - lacks most of the conserved residues essential for binding the metal cofactor & hence for dihydropyrimidinase activity Compartment: cytoplasm (probable)

Related

anti-collapsin response mediator protein-5 (anti-CRMP-5) dihydropyrimidinase; DHP; DHPase; dihydropyrimidine amidohydrolase; hydantoinase (DPYS)

Properties

SIZE: entity length = 564 aa MW = 61 kD COMPARTMENT: cytoplasm MOTIF: Thr phosphorylation site {T509} Thr phosphorylation site {T514} Thr phosphorylation site {T516} Ser phosphorylation site {S534}

Database Correlations

OMIM 608383 UniProt Q9BPU6 Pfam PF01979 Entrez Gene 56896 Kegg hsa:56896

References

UniProt :accession Q9BPU6