creatinine

Physiology: - creatinine is formed through non-enzymatic dehydration of tissue creatine - muscle contains 98% of total body creatine - creatinine is not recycled, or used in metabolism, thus represents a waste product of creatine metabolism - creatinine is filtered by glomeruli, but is not reabsorbed to an appreciable extent under normal conditions - creatinine is also excreted by the proximal tubules in normal individuals adding & an additional 10-40% to the total creatinine in urine Pathology: - in congestive heart failure & in uncontrolled diabetes, tubular reabsorption of creatinine may occur Laboratory: - creatinine in gastric fluid - creatinine in vitreous fluid - creatinine in synovial fluid - creatinine in dialysis fluid - creatinine in peritoneal dialysis fluid - creatinine in CSF - creatinine in blood - creatinine in serum/plasma - creatinine/BUN ratio - creatinine in stool - creatinine in urine - urine creatinine ratio - creatinine clearance

Related

creatine creatinine in 24 hour urine creatinine in body fluid

Properties

COMPARTMENT: plasma serum

References

Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 164