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creatine
Pharmacology:
- derived primarily from meats, poultry, & seafood
Indications:
- used as a sports supplement
- dietary creatine may lower risk for depression (RR=0.7) [2]
- protective association stronger in women (RR=0.62 than men RR=0.72)
Pharmacokinetics:
- metabolized to creatinine Interactions:
- can increase serum creatinine
Laboratory:
- creatine in amniotic fluid
- creatine in CSF
- creatine in serum/plasma
- creatine in urine
- creatine in vitreous fluid
Mechanism of action:
- taken in the hope of increasing creatine phosphate
Interactions
molecular events
Related
creatinine
X-linked creatine deficiency syndrome
Specific
creatine phosphate; phosphocreatine
General
carboxylate
guanidine
intermediary metabolite
Database Correlations
PUBCHEM correlations
References
- Prescriber's Letter 9(5):28 2002
- Bakian AV, Huber RS, Scholl L et al.
Dietary creatine intake and depression risk among U.S. adults.
Transl Psychiatry 2020 Feb 3;
PMID: 32066709
https://www.nature.com/articles/s41398-020-0741-x