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cramp fasciculation syndrome
Etiology:
- autoimmune [2]
- idiopathic (most cases)
Epidemiology:
- rare
Pathology:
- peripheral nerve hyperexcitability disorder
Clinical manifestations:
- fasciculations
- muscle cramps
- myalgia
- muscle stiffness
- fatigue
- anxiety
- exercise intolerance
- globus sensations
- paraesthesias
- hyperreflexia
Special laboratory:
- electromyography: fasciculations only abnormality
Management:
- anticonvulsants
- carbamazepine, gabapentin, pregabalin
- immunosuppressive agents
- plasmapheresis
General
peripheral nerve disease; peripheral neuropathy
syndrome
References
- Wikipedia: Cramp fasciculation syndrome
http://en.wikipedia.org/wiki/Cramp_fasciculation_syndrome
- Office of Rare Diseases
Genetic and Rare Diseases Information Center (GARD)
Cramp-fasciculation syndrome.
http://rarediseases.info.nih.gov/gard/6205/cramp-fasciculation-syndrome/resources/1