Search
cerebral cortical atrophy
Etiology:
- older age
- Alzheimer's disease & other dementias
- alcohol use disorder
Pathology:
- associated with widened sulci/narrow gyri
- predisposes patients to subdural hematoma even with minor head trauma
- enlargement of space between dura mater & brain
- tenses bridging veins increasing risk of hemorrhage
- cerebral cortical atrophy occurs slower in elderly >= 80 years of age with preserved episodic memory [1]
Related
cerebral cortex
General
atrophy
References
- Samuelson K
Next step in Alzheimer's research: Brain shrinkage rates.
SuperAger brains shrink more slowly than peers' brains.
Northwestern Now. April 04, 2017
https://news.northwestern.edu/stories/2017/april/alzheimers-research-superagers-brain-shrinkage/
- Cook AH, Sridhar J, Ohm D et al
Rates of Cortical Atrophy in Adults 80 Years and Older With
Superior vs Average Episodic Memory
JAMA. 2017;317(13):1373-1375
PMID: 28384819
http://jamanetwork.com/journals/jama/article-abstract/2614177