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Flurandrenolide Topical (Cordran)
Indications:
- relief of inflammatory dermatoses (dermatitis)
- allergic dermatitis
- atopic dermatitis, contact dermatitis [3]
- seborrheic dermatitis
- dandruff
- discoid lupus
- granuloma annulare
- psoriasis
- pruritus, anal pruritus
- lichen simplex chronicus
- alleriges
- cutaneous T-cell lymphoma [3]
Dosage:
- apply BID/TID
cream/ointment 0.025% & 0.05% (30g, 60g).
Medium potency (0.025%).
Adverse effects:
- uncommon (< 1%)
- burning, itching, irritation, dryness, folliculitis, hypertrichosis, acne, hypopigmentation, perioral dermatitis, allergic contact dermatitis, skin atrophy,, striae, miliaria, intracranial hypertension, maceration of skin, suppression of hypothalamic-pituitary-adrenal axis, Cushing's syndrome, growth retardation, secondary infection
Mechanism of action:
- anti-inflammatory; topical glucocorticoid class 4, class 5 [4]
Interactions
drug adverse effects of glucocorticoids
monitor with drug (more general terms)
General
flurandrenolide
topical glucocorticoid (topical steroid)
Properties
MISC-INFO: pregnancy-category C
safety in lactation ?
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Kaiser Permanente Northern California Regional Drug
Formulary, 1998
- Deprecated Reference
- Medical Knowledge Self Assessment Program (MKSAP) 17,
American College of Physicians, Philadelphia 2015
- Department of Veterans Affairs, VA National Formulary