COP9 signalosome complex subunit 7a (signalosome subunit 7a, SGN7a, JAB1-containing signalosome subunit 7a, COPS7a, dermal papilla-derived protein 10, JAB7a, CSN7a, DERP10)

Function: 1) component of the COP9 signalosome complex 2) in the complex, interacts with COPS1,COPS2, COPS4, COPS5, COPS6, COPS8 3) interacts with PMF1 4) interacts with the translation initiation factor EIF3S6 5) interacts with CK2, PKD, ID3 6) phosphorylated by CK2 & PKD kinases 7) phosphorylated upon DNA damage, probably by ATM or ATR Structure: - belongs to the CSN7/EIF3M family, CSN7 subfamily - contains 1 PCI domain Compartment: cytoplasm, nucleus Expression: - widely expressed - expressed at high level in brain, heart, skeletal muscle

General

dermal papilla-derived protein protein subunit

Properties

SIZE: MW = 30 kD entity length = 275 aa COMPARTMENT: cytoplasm cell nucleus MOTIF: PCI {52-156} coiled coil {185-233}

Database Correlations

UniProt Q9UBW8 Pfam PF01399

References

UniProt :accession Q9UBW8