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copper in serum
Normal range:
- 70-155 ug/dL (11-24.3 umol/L)
Clinical significance:
- see Cu+/Cu+2
- copper deficiency
- may be associated with Menke's disease
- copper excess
a) relatively non-toxic
b) may be associated with Wilson's disease
Increases:
- infection
- inflammation
- pregnancy
- leukemia
- biliary cirrhosis
- typhoid fever
- Hodgkin's disease
- thalassemia major & thalassemia minor
- acute myocardial infarction
- hypothyroidism
- hyperthyroidism
- connective tissue diseases
- rheumatic fever
- systemic lupus erythematosus
- trauma
- malignant neoplasms
- dialysis
Decreases:
- Wilson's disease
- celiac disease
- cystic fibrosis
- nephrotic syndrome
- Menke's syndrome
- burns
- protein malnutrition
- chronic ischemic heart disease
Method:
- flame AAS (most widely used)
Related
copper deficiency
Cu+/Cu+2
General
copper in body fluid
References
- Medical Knowledge Self Assessment Program (MKSAP) 11, 15,
American College of Physicians, Philadelphia 1998, 2009
- Henry's Clinical Diagnosis & Management by Laboratory Methods,
21st edition, McPherson RA & Pincus MR (es), W.B. Saunders Co.,
Philadelphia, PA. 2007, pg 386
- Clinical Guide to Laboratory Tests, 4th edition, HB Wu ed,
WB Saunders, Philadelphia, 2006
- Copper, Serum
Laboratory Test Directory ARUP: 20096
- Copper, Serum Free (Direct)
Laboratory Test Directory ARUP: 20596
- Panel of 3 tests
Laboratory Test Directory ARUP: 20598