complement fixation

Indications: - widely used in laboratories for the detection of antigen or antibodies Principle: - firmly attaching or fixing complement in serum by antigen- antibody complex so that it is no longer available additional complement-mediated functions - in complement-fixation tests, the 2nd system generally serves as an indicator of complement fixation in the 1st system, i.e. erythrocytes plus a hemolysin

References

Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999