colonic ulceration

Etiology: - NSAIDs cause ulcers in the cecum & right colon - isolated rectal ulcers are caused by a) ischemia b) solitary rectal ulcer syndrome (SRUS) c) radiation d) fecal impaction - infectious causes include tuberculosis & amebiasis Clinical manifestations: - abdominal pain - hematochezia - chronic gastrointestinal bleeding Special laboratory: - colonoscopy with endoscopic biopsy to rule out colon cancer Differential diagnosis: - inflammatory bowel disease - colon cancer Complications: - intestinal perforation (rare) Management: - stop NSAID - treat constipation - recognition of the patient with SRUS

Related

Crohn's disease; terminal ileitis; regional enteritis; granulomatous enteritis; chronic cicatrizing enteritis ulcerative colitis (UC)

References

Nagar AN Isolated colonic ulcers: diagnosis and management. Curr Gastroenterol Rep. 2007 Oct;9(5):422-8. PMID: 17991345