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colon cancer genotyping
Indications:
- colorectal carcinoma
Specimen:
1) colon tissue
2) whole blood (ACD or EDTA)
3) store body fluid at 4 degrees C
4) store tissue at -20 degrees C or below
Genetics:
- associated genetic aberrations:
- adenomatous polyposis coli (FAP) gene
- mutated in colon carcinoma (MCC) tumor suppressor gene
- deleted in colon carcinoma (DCC) tumor suppressor gene
Related
adenocarcinoma of the colon &/or rectum
APC gene mutation
Deleted in Colon Carcinoma [DCC] tumor suppressor gene
familial adenomatous polyposis [FAP] gene
Mutated in Colon Carcinoma [MCC] tumor suppressor gene
General
genotyping (allele testing)
References
Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed.,
W.B. Saunders, 1995
Components
APC gene mutation