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collagenase clostridium histolyticum (CCH, Xiaflex, Qwo)

Indications: - Dupuytren's contracture - Peyronie's disease (FDA-approved Ded 2013) Dosage: - 0.58 mg into the contracted collagen cord - injections every 30-day intervals - joint manipulation one day after injection

Related

collagenase ointment (SANTYL)

General

collagenase musculoskeletal system agent

References

  1. Hurst LC et al, Injectable Collagenase Clostridium Histolyticum for Dupuytren's Contracture N Engl J Med 2009, 361:968-979 PMID: 19726771 http://content.nejm.org/cgi/content/short/361/10/968
  2. FDA News Release: Dec. 6, 2013 FDA approves first drug treatment for Peyronie's disease. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm377849.htm