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colistimethate (Coly-Mycin M)

Indications: - treatment of acute or chronic infections due to sensitive strains of certain Gram-negative bacilli, particularly Pseudomonas aeruginosa - bronchiectasis with Pseudomonas aeruginosa infection [2] Contraindications: - not FDA approved for use as a liquid to be inhaled via nebulizer - once Colistimethate is mixed into a liquid form, it breaks down into other chemicals that can damage lung tissue - I-neb adaptive aerosol delivery system apparently ok [2]

General

colistin

Database Correlations

PUBCHEM correlations

References

  1. FDAMedwatch http://www.fda.gov/medwatch/safety/2007/safety07.htm#Colistimethate
  2. Ingram I Inhaled Antibiotic for Bronchiectasis Shows Benefit ... and Then It Doesn't One negative trial in the phase III PROMIS program blamed squarely on the COVID-19 pandemic. MedPage Today September 12, 2024 https://www.medpagetoday.com/meetingcoverage/ers/111929