Search
cold injury syndrome
Etiology:
- hypothermia
Epidemiology:
- infants & newborns
- winter months
Clinical manifestations:
- cold skin & limbs,
- sleepiness, hypotonia, inactivity (92%)
- cyanosis with bradycardia, bradypnea, & apnea (78%)
- disseminated intravascular coagulation (63%)
Complications:
- death from
- pulmonary hemorrhage
- respiratory distress syndrome [1]
- pneumonia
- sepsis
- sudden infant death syndrome (SIDS) [2]
- neurodevelopmental disorder (67%)
- cognitive impairment (4%)
Laboratory:
- complete blood count (CBC)
- plasma D-dimer
Management:
- intensive care unit
General
cold injury
hypothermia
syndrome
References
- Culic S.
Cold injury syndrome and neurodevelopmental changes in
survivors.
Arch Med Res. 2005 Sep-Oct;36(5):532-8.
PMID: 16099334
- Goldsmith JR, Arbeli Y, Stone D
Preventability of neonatal cold injury and its contribution
to neonatal mortality.
Environ Health Perspect. 1991 August; 94: 55-59
PMID: 1954941
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567975/