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codeine/promethazine (Phenergan with codeine)
DEA-controlled substance: class 5.
Indications:
- temporary relief of coughs & upper respiratory tract symptoms associated with allergy or the common cold
Contraindications:
1) concurrent use of MAO inhibitors
2) increased intracranial pressure
3) depressed ventilation
Dosage:
1) adults & children > 12 years of age:
-> 5-10 mL every 4-6 hours PRN (10-20 mg of codeine/dose)
2) children 6-12 years: 2.5-5 mL every 4-6 hours PRN (5-10 mg of codeine/dose)
3) children 2-6 years: 1.25-2.5 mL every 4-6 hours PRN (2.5-5 mg of codeine/dose)
Syrup: promethazine HCl 6.25 mg & codeine phosphate 10 mg/5 mL (120 mL, 240 mL)
Adverse effects: see promethazine & codeine
General
Ear nose throat combination
References
- The Pharmacological Basis of Therapeutics, 9th ed.
Gilman et al, eds. Permagon Press/McGraw Hill, 1996
- Kaiser Permanente Northern California Regional Drug
Formulary, 1998
Components
codeine
promethazine (Phenergan, Farganesse)