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coagulation factor X autoantibody

Autoantibody to factor X enhances clearance of factor X from the circulation. In vitro coagulation tests correct with addition of normal plasma because the autoantibody does not interact with the active site of an enzyme.

Interactions

drug adverse effects of antithrombotic agent(s)

Related

coagulation factor X; Stuart factor; Stuart-Prower factor; contains: factor X light chain; factor X heavy chain; activated factor Xa heavy chain (F10)

General

autoantibody coagulation factor antibody

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998