coagulation factor VII autoantibody

Autoantibody to factor VII enhances clearance of factor VII from the circulation. In vitro coagulation tests correct with addition of normal plasma because the autoantibody does not interact with the active site of an enzyme.

Related

coagulation factor VII inhibitor in plasma coagulation factor VII; proconvertin; serum prothrombin conversion accelerator; SPCA; Eptacog alfa; contains: factor VII light chain; factor VII heavy chain (F7)

General

autoantibody coagulation factor antibody

References

Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998