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staphylocoagulase (clumping factor)

Staphylococcus aureus is distinguished from other Staphylococci by the production of coagulase. 2 antigenically distinct forms [2] 1) cell-wall bound 2) free Plasma factor may induce release of cell-wall bound coagulase Coagulase-thrombin complex forms & cleaves fibrinogen to form fibrin clot.

General

bacterial protein

References

  1. PROSITE :accession PS00429
  2. Clinical Diagnosis & Management by Laboratory Methods, 19th edition, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1996, pg 1137