acyl coenzyme-A [CoA] synthetase or acyl coenzyme-A [CoA] ligase

acyl CoA synthetases catalyze the initial reaction in fatty acid metabolism, by forming a thioester with CoA

Specific

acetoacetyl-CoA synthetase (acyl-CoA synthetase family member 1, protein sur-5 homolog, AACS, ACSF1) acetyl coenzyme A synthetase acetyl-coenzyme A synthetase 2-like, mitochondrial; acetyl-CoA ligase 2; acetyl-CoA synthetase 2; acyl-CoA synthetase short-chain family member 1 (ACSS1, ACAS2L, KIAA1846) acetyl-coenzyme A synthetase, cytoplasmic (acetate-CoA ligase, acyl-activating enzyme, acetyl-CoA synthetase, ACS, AceCS, acyl-CoA synthetase short-chain family member 2, ACSS2, ACAS2) acyl-CoA synthetase family member 2, mitochondrial (ACSF2) acyl-CoA synthetase family member 3, mitochondrial (ACSF3) acyl-CoA synthetase family member 4 (protein NRPS998, AASDH, ACSF4, U26, HSPC318) acyl-coenzyme A synthetase ACSM1, mitochondrial (acyl-CoA synthetase medium-chain family member 1, middle-chain acyl-CoA synthetase 1, butyrate-CoA ligase 1, butyryl coenzyme A synthetase 1, lipoate-activating enzyme, ACSM1, BUCS1, LAE, MACS1) acyl-coenzyme A synthetase ACSM2A, mitochondrial (scyl-CoA synthetase medium-chain family member 2A, middle-chain acyl-CoA synthetase 2A, butyrate-CoA ligase 2A, butyryl coenzyme A synthetase 2A, ACSM2A, ACSM2, MACS2) acyl-coenzyme A synthetase ACSM2B, mitochondrial (acyl-CoA synthetase medium-chain family member 2B, middle-chain acyl-CoA synthetase 2B, butyrate--CoA ligase 2B, butyryl coenzyme A synthetase 2B, xenobiotic/medium-chain fatty acid-CoA ligase HXM-A, ACSM2B, ACSM2, HYST1046) acyl-coenzyme A synthetase ACSM3, mitochondrial (acyl-CoA synthetase medium-chain family member 3, middle-chain acyl-CoA synthetase 3, butyrate-CoA ligase 3, butyryl coenzyme A synthetase 3, protein SA homolog, ACSM3, SAH) acyl-coenzyme A synthetase ACSM4, mitochondrial (ACSM4) acyl-coenzyme A synthetase ACSM5, mitochondrial (ACSM5, MACS3) bifunctional coenzyme A synthase; CoA synthase; NBP; POV-2; includes: phosphopantetheine adenylyltransferase; dephospho-CoA pyrophosphorylase; pantetheine-phosphate adenylyltransferase; PPAT; dephospho-CoA kinase; DPCK; dephosphocoenzyme A kinase; DPCOAK (COASY) eicosanoid CoA ligase fatty-acid CoA ligase succinyl CoA synthetase (GDP-formining)

General

ligase or synthetase membrane protein

Properties

COMPARTMENT: smooth endoplasmic reticulum outer mitochondrial membrane MOTIF: membrane region active site