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central nervous system (CNS) tuberculoma

Etiology: - tuberculous meningitis: may occur during or after treatment Pathology: - initial pathology is same as tuberculous meninigitis - instead of invading the subarachnoid space, tuberculomas continue to grow, walled off from the brain parenchyma by a dense fibrous capsule - lesions may be < 1 cm to several centimeters in diameter - lesions may ne singlular or multiple - intracranial mass lesion effects occur Radiology: - magnetic resonance imaging with gadolinium enhancement (see [2]) Complications: - liquification of the caseous core results in a tuberculous abscess; these patients tend to clinically worse - intracranial mass lesion effects

Related

tuberculous meningitis

Specific

meningeal tuberculoma

General

tuberculoma

References

  1. Goldstein MA and Harden CL CNS tuberculoma http://professionals.epilepsy.com/page/mycobac_cns.html
  2. Catano JC Cerebral tuberculoma N Engl J Med 2007; 357:2166 http://www.nejm.org/doi/full/10.1056/NEJMicm066067