CCR4-NOT transcription complex subunit 3 (CCR4-associated factor 3, leukocyte receptor cluster member 2, CNOT3, KIAA0691, NOT3)

Function: - subunit of CCR4-NOT core complex - binds TIP120B Structure: belongs to the CNOT2/3/5 family Compartment: cytoplasm, nucleus (probable) Alternative splicing: named isoforms=3 Expression: - ubiquitous - highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, lung, peripheral blood leukocytes

General

phosphoprotein protein subunit

Properties

SIZE: entity length = 753 aa MW = 82 kD COMPARTMENT: cytoplasm cell nucleus MOTIF: Ser phosphorylation site {S299} proline-rich region SITE: 314-395 MOTIF: proline residue (SEVERAL) serine-rich region {397-425} MOTIF: serine residue (SEVERAL) proline-rich region SITE: 457-655 MOTIF: proline residue (SEVERAL)

Database Correlations

OMIM 604910 UniProt O75175 PFAM correlations

References

UniProt :accession O75175