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Clostridium
Anaerobes normally present in the intestinal tract.
Pathology:
- includes both pathogenic & nonpathogenic strains
Laboratory:
- gram stain: gram-positive rods
Comparative biology:
- nonpathogenic Clostridia (17 strains) normally found in human intestinal flora can suppress immunologically mediated disease in mice
- the Clostridial strains induce CD4+FOXP3+ regulatory T-cells
- promise for treatment of inflammation & allergy
Specific
Clostridium baratii
Clostridium botulinum
Clostridium chauvoei
Clostridium difficile; Clostridioides difficile
Clostridium novyii
Clostridium perfringens
Clostridium septicum
Clostridium sordellii
Clostridium tetani
General
Eubacteriales (Clostridiales)
Properties
KINGDOM: monera
DIVISION: SCHIZOMYCETES
References
- Atarashi K, Tanoue T, Oshima K et al
Treg induction by a rationally selected mixture of Clostridia
strains from the human microbiota.
Nature. 2013 Aug 8;500(7461):232-6
PMID: 23842501