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cleft palate

Pathology: - congenital fissure or cleft in the middle or median line of the palate, often associated with cleft lip - cleft palate often occurs as a feature of a syndrome Complications: - cleft palate is linked to increased mortality & morbidity [2] compared with the unaffected population* - increased risk for death (RR=3.4) - increased risk for intellectual disability (RR=11.5) - increased risk for anxiety disorders (RR=2.9) - increased risk for autism spectrum disorder (RR=6.6) - increased risk for severe learning disabilities, cerebral palsy, epilepsy, musculoskeletal disorders * cleft lip is not linked to increased mortality & morbidity Management: - palatoplasty

Related

cleft lip fissure (cleft)

Specific

uranostaphyloschisis

General

orofacial cleft

Database Correlations

OMIM 241850

References

  1. Stedman's Medical Dictionary 27th ed, Williams & Wilkins, Baltimore, 1999
  2. Berg E, Haaland OA, Feragen KB et al Health Status Among Adults Born With an Oral Cleft in Norway. JAMA Pediatr. Published online September 26, 2016. PMID: 27668670 http://archpedi.jamanetwork.com/article.aspx?articleid=2556204
  3. National Institute of Dental and Craniofacial Research Cleft Lip & Palate https://www.nidcr.nih.gov/health-info/cleft-lip-palate