cinoxacin (Cinobac)

Indications: - treatment of bacterial infections due to susceptible organisms - initial & recurrent urinary tract infections in adults Dosage: - 500 mg PO BID - at least 2 hours before or 2 hours after antacids containing magnesium or aluminum, iron, or zinc Dosage adjustment in renal failure: - creatinine clearance (mL/min/1.73 m2) > 80: 500 mg BID 50-80: 250 mg TID 20-50: 250 mg BID < 20: 250 mg QD Antimicrobial activity: - Escherichia coli - Proteus mirabilis - Proteus vulgaris - Klebsiella species (including K.pneumoniae) - Enterobacter species

References

- RxList http://www.rxlist.com/cinobac-drug.htm