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cilastatin
Cilastatin inhibits the degradation of imipenem by a renal tubular dipeptidase. It is marketed in combination with imipenem (Primaxin).
Related
imipenem cilastatin (Primaxin)
General
amide
amine
carboxylate
enzyme inhibitor
Properties
INHIBITS: dipeptidase
Database Correlations
PUBCHEM correlations
References
- The Pharmacological Basis of Therapeutics, 8th ed.
Gilman et al, eds. Permagon Press/McGraw Hill pg 1092
- Harrison's Principles of Internal Medicine, 13th ed.
Companion Handbook. Isselbacher et al (eds),
McGraw-Hill Inc. NY, 1995, pg 163.
Component-of
cilastatin/imipenem
imipenem cilastatin/relebactam (Recarbrio)