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chronic renal failure stage 5

Management: - ACE inhibitor or ARB delays progression to ESRD but not mortality [3] - in patients aged > 75 years with high comorbidity, survival advantage conferred by hemodialysis over conservative management is likely to be small [2] - age > 75 years & female gender predicts better survival in conservatively managed patients - initiation of dialysis is often associated with a significant functional decline

Related

end-stage renal disease (ESRD)

General

chronic renal failure (CRF)

References

  1. Da Silva-Gane M, Wellsted D, Greenshields H et al Quality of life and survival in patients with advanced kidney failure managed conservatively or by dialysis. Clin J Am Soc Nephrol. 2012 Dec;7(12):2002-9. PMID: 22956262
  2. Chandna SM, Da Silva-Gane M, Marshall C, Survival of elderly patients with stage 5 CKD: comparison of conservative management and renal replacement therapy. Nephrol Dial Transplant. 2011 May;26(5):1608-14. PMID: 21098012
  3. Ku E, Inker LA, Tighiouart H et al. Angiotensin-Converting Enzyme Inhibitors or Angiotensin-Receptor Blockers for Advanced Chronic Kidney Disease : A Systematic Review and Retrospective Individual Participant-Level Meta-analysis of Clinical Trials. Ann Intern Med. 2024. July 2 PMID: 38950402 Review. https://www.acpjournals.org/doi/10.7326/M23-3236
  4. Centers for Disease Control and Prevention (CDC) Chronic Kidney Disease (CKD) Surveillance Project https://nccd.cdc.gov/ckd/Help.aspx?section=F#3