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chronic myelogenous leukemia genotyping

Indications: - chronic myelogenous leukemia Specimen: 1) bone marrow 2) whole blood (ACD or EDTA) 3) store body fluid at 4 degrees C 4) store tissue at -20 degrees C or below Genetics: - associated genetic aberrations: - chromosomal translocation t9q34.1:22q11 (Philadelphia chromosome) Method: bcr/abl mRNA by RT-PCR

Related

chromosomal translocation t9q34.1:22q11 (Philadelphia chromosome; bcr/abl) chronic myeloid leukemia (CML, granulocytic leukemia)

Specific

BCR-ABL1 fusion protein in blood/tissue

General

genotyping (allele testing)

References

  1. Clinical Guide to Laboratory Tests, 3rd ed. Teitz ed., W.B. Saunders, 1995
  2. Medical Knowledge Self Assessment Program (MKSAP) 16, American College of Physicians, Philadelphia 2012