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chronic liver disease

Includes chronic diseases of the liver. Laboratory: - complete blood count (CBC) - iron studies - serum ferritin (rule out hemochromatosis) * also see liver disease & cirrhosis Management: - prevention - NSAID use (RR = 0.74), especially aspirin (RR = 0.55), associated with reduced risk of death from chronic liver disease [1] - treatment of chronic pain should include physical therapy because it will not exacerbate chronic liver disease [3] - immunizations [3] - hepatitis A vaccine - hepatitis B vaccine - pneumococcal vaccines - annual influenza vaccine

Related

hospice guidelines for determining prognosis, liver disease liver

Specific

chronic hepatitis cirrhosis genetic disease of the liver portal systemic encephalopathy (PSE) steatosis; fatty liver; nonalcoholic fatty liver disease (NAFLD); metabolic dysfunction-associated steatotic liver disease (MASLD)

General

chronic disease liver disease

References

  1. Sahasrabuddhe VV et al Nonsteroidal Anti-inflammatory Drug Use, Chronic Liver Disease, and Hepatocellular Carcinoma JNCI J Natl Cancer Inst (2012) November 28 PMID: 3197492 http://jnci.oxfordjournals.org/content/early/2012/11/28/jnci.djs452.abstract - Levy IG and Pim CP An Aspirin a Day: The Allure (and Distraction) of Chemoprevention JNCI J Natl Cancer Inst (2012) November 28 PMID: 23197493 http://jnci.oxfordjournals.org/content/early/2012/11/28/jnci.djs462.full
  2. Tripodi A, Mannucci PM. The coagulopathy of chronic liver disease. N Engl J Med. 2011 Jul 14;365(2):147-56. Review. PMID: 21751907
  3. Medical Knowledge Self Assessment Program (MKSAP) 19, American College of Physicians, Philadelphia 2021.