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chronic active hepatitis (CAH)
Chronic inflammation of the liver involving the portal tracts & periportal parenchyma.
Etiology:
1) autoimmune hepatitis
2) viral hepatitis
Management:
- chronic hepatitis B infection [2]
- lamivudine 100 mg PO QD
a) well tolerated
b) may reduce inflammation
c) may retard progression to cirrhosis
d) may reduce serum hepatitis B DNA levels
e) therapy may be necessary for indefinite period
Specific
chronic active hepatitis B
General
viral hepatitis
chronic hepatitis
References
- Manual of Medical Therapeutics, 28th ed, Ewald &
McKenzie (eds), Little, Brown & Co, Boston, 1995, pg 371
- Journal Watch vol 19 #22, pg 173-74, Nov 15, 1999