chromosomal translocation t(Y;4)(q11.2;q21)

- chromosomal translocation t(Y;4)(q11.2;q21) involving MAPK10 is a cause of epileptic encephalopathy Lennox-Gastaut type - causes MAPK10 truncation

Properties

GENERAL: chromosomal translocation FORM: t(Y;4)(q11.2;q21) LOCUS: human Y-chromosome Q11 human chromosome-4 Q21 PATHOLOGY: acute leukemia SPLICED-GENES: MAPK10/JNK3

References

UniProt :accession Q9P2F6