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chromosomal translocation t(9;18)(p13;q11.2) (acute lymphoblastic leukemia)
- chromosomal translocation t(9;18)(p13;q11.2) involving ZNF521 with PAX5 is found in acute lymphoblastic leukemia
- translocation generates the PAX5-ZNF521 oncogene consisting of N-terminus of PAX5 & C-terminus of ZNF521
Properties
GENERAL: chromosomal translocation
RELATED: neuronal PAS domain-containing protein 3
FORM: t(9;18)(p13;q11.2)
LOCUS: human chromosome-9 P13
human chromosome-18 Q11.2
PATHOLOGY: acute lymphoblastic leukemia (ALL)
References
UniProt :accession Q8IXF0