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chromosomal translocation t8q24.1:14q32 (B-cell leukemia, Burkitt's lymphoma)


Properties

GENERAL: chromosomal translocation RELATED: immunoglobulin heavy chain gene acute lymphoblastic leukemia, L3 non-Hodgkin's lymphoma Burkitt's lymphoma c-myc proto-oncogene FORM: t8q24.1:14q32 LOCUS: human chromosome-8 Q24 human chromosome-14 Q32 PATHOLOGY: acute lymphoblastic leukemia, L3 Burkitt's lymphoma ABERRANT-GENE: c-myc proto-oncogene immunoglobulin heavy chain gene

References

  1. Cotran et al Robbins Pathologic Basis of Disease, W.B. Saunders Co, Philadelphia, PA 1989 pg 288
  2. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998