chromosomal translocation t8p11:16p13 (acute leukemia)

- translocation t(8;16)(p11;p13) with CREBBP; fusion protein MYST3-CREBBP may induce leukemia by inhibiting RUNX1-mediated transcription

Properties

GENERAL: chromosomal translocation FORM: t8p11:16p13 LOCUS: human chromosome-8 P11 human chromosome-16 P13 PATHOLOGY: acute leukemia ABERRANT-GENE: CREBBP gene MOZ gene

References

UniProt :accession Q92794